IN THE RED JOURNAL THIS MONTH
Serum and Colonic Mucosal Immune Markers in Irritable Bowel Syndrome
Chang and colleagues explore the role of the immune system in non-post-infectious IBS (non-PI-IBS). It is now largely accepted that, in the context of post-infectious IBS, engagement of the immune system leads to many of the functional changes and subtle inflammatory changes that characterize that condition. In this study with a relatively large number of individuals with non-PI-IBS, most inflammatory immune activation markers in serum or sigmoid mucosa were no different in patients as compared with controls--with two key exceptions.
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