Analysis links PPIs to higher risk of C. diff infection

An analysis of 42 observational studies found proton pump inhibitors raise the risk of Clostridium difficile infection, especially for patients taking antibiotics, U.K. researchers reported in the American Journal of Gastroenterology. Researchers said PPIs should be avoided by patients taking antibiotics “unless there are clear gastrointestinal indications for acid-suppression therapy.” Medscape (free registration)/Reuters (5/14)