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Study links gene mutation to risk for multiple colon polyps

The heritable APC genetic mutation was more strongly linked than the MUTYH mutation to a high risk for multiple colorectal polyps in a study by researchers at Brigham and Women’s Hospital. In people with 1,000 or more polyps, 80% also had the APC mutation, but only 2% had the MUTYH mutation. “The study’s findings may be helpful in counseling people with familial adenomatous polyposis and family members, and could lead to changes in the future in screening for polyps in people with [the condition] and families of these patients,” said gastroenterologist David Feldman. HealthDay News (7/31)

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