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Study links mutation to gastrointestinal illnesses

A mutation in the GUCY2C gene that affects intestinal chloride and water secretion may be linked to chronic diarrhea, Crohn’s disease, irritable bowel syndrome and other diagnoses, according to a study from Norway. Haukeland University Hospital researchers conducted whole-genome sequencing on 32 members of a Norwegian family who suffered with chronic diarrhea. They found all affected patients carried a missense mutation in the gene. MedPage Today (free registration) (3/22)

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