Colorectal Cancer Prevention Action Plan and RFAs

The ACG Colorectal Cancer Prevention Action Plan is an ambitious, multi-faceted effort approved by the ACG Board of Trustees in 2004. Under this plan, the College has devoted significant resources to large research grants on specific clinically important topics in colorectal cancer. The foundation of the Action Plan is ACG’s conviction that clinical gastroenterology take up the challenge to take a very close look at today’s preferred colorectal cancer prevention method, colonoscopy, and to make it even better, and to encourage development of new prevention strategies. The Action plan contains two major components: educational outreach to the public and to the physician community, as well as a substantial commitment to research about improvements to colonoscopy, and evaluation of other screening methodologies. Additionally, under the auspices of the Action Plan, the College provides financial support for ongoing targeted patient and physician education efforts regarding colorectal cancer screening.

2005 ACG Colorectal Cancer Prevention Action Plan RFA
The goal of the first CRC RFA was to determine the prevalence, size, shape and histology of flat colorectal neoplasms in the United States.
One Grant of $100,000
Charles J. Kahi, MD, MSc Indiana University School of Medicine and Roudebush VA Medical Center, Indianapolis, IN. A multi-center study, “Chromocolonoscopy for the Detection of Flat Adenomas in Routine Colorectal Cancer Screening.”
2007 ACG Colorectal Cancer Prevention Action Plan RFA
In developing the 2007 RFA, the Institute recognized that in spite of multiple efforts to promote colorectal cancer screening, utilization rates remain low and adherence to surveillance guidelines is highly variable. ACG’s goal was to promote research geared toward improving the quality of colorectal cancer screening and/or surveillance, with the ultimate goal of reducing colorectal cancer incidence and mortality.
Two Awards Totaling $264,652
Cynthia Ko, MD, University of Washington, Seattle, “Colonoscopy Quality and Outcomes in Clinical Practice”Linda Rabeneck, MD, MPH, MACG, Sunnybrook Regional Cancer Centre, Toronto, “New or Missed Colorectal Cancer After Colonoscopy”

2012-2013 RFA for Colorectal Cancer Prevention Research

In 2012, the Institute issued the final RFA in the series on Colorectal Cancer Prevention to support a one-year project of $125,000 “to promote research to better understand drivers of variation in colorectal cancer screening process and outcomes of care, and to employ these findings to ultimately improve detection of colorectal neoplasm.” The RFA specifically sought proposals to develop and validate educational tools or other methods that result in improved detection of colorectal neoplasia.

In 2013, the ACG Institute presented a grant of $125,000 to a team of researchers led by Michael B. Wallace, MD, MPH, FACG, of Mayo Clinic-Jacksonville, for the Endoscopic Quality Improvement Project-2 (EQUIP-2) to Improve Adenoma Detection in Screening and Surveillance Colonoscopy validation study.

EQUIP-2 seeks to evaluate the effectiveness of a quality improvement training program to improve adenoma detection in screening and surveillance colonoscopy. In the original study, EQUIP-1, a single-center study including 15 GI physicians was conducted, in which statistically significant improvement in adenoma detection rates (ADR) was observed after a training intervention of a series of 1-hour classes and ongoing monitoring and feedback. The aim of EQUIP-2 is to assess whether these findings will be validated in a larger, multi-center practice setting using GIQuIC, a national endoscopic quality database co-sponsored by ACG and ASGE.