P1181 Pathologic Findings on Repeat Biopsy in Children With Celiac Disease on a Gluten-Free Diet
Author insight from Michael J Pettei, MD, PhD, Cohen Children’s Medical Center of New York, North Shore LIJ Health System, Lake Success, NY
What’s new here and important for clinicians?
In contrast to recent adult studies demonstrating a relatively low rate of full recovery of the small bowel mucosa in celiac disease (CD) even after long-term gluten-free diet (GFD), children with CD seem to more frequently recover fully and in less time on the GFD. This affirms the pediatric guidelines which only call for a solitary initial biopsy in uncomplicated CD. It raises questions whether the variation noted is due to inherent differences in the nature of CD, related to the pre-diagnosis length of time with CD, or differences in the application of a GFD between adult and pediatric patients.
What do patients need to know?
Pediatric patients and their families need to know that application of the GFD should generally result in complete healing of the small bowel lesion.
Michael J Pettei, MD, PhD, Cohen Children’s Medical Center of New York, North Shore LIJ Health System, Lake Success, NY
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