**EMBARGOED All research presented at the ACG Annual Scientific Meeting is strictly embargoed until Monday, October 19, 2015 at 8 AM (EDT).

Poster 220 Superglue to the Rescue: Use of Cyanoacrylate Spray to Stop Bleeding From Large Peptic Ulcer 

Author Insights from Siddharth Javia, MD; Nirav C. Thosani, MD, MHA, University of Texas Health Science Center at Houston

What’s new here and important for clinicians?

We report successful use of n-butyl-2-cyanoacrylate glue spray to control recurrent bleeding from a large peptic ulcer invading into muscularis propria, for which epinephrine injection, hemoclip application and thermal therapy were unsuccessful at controlling bleeding.

What do patients need to know?

Ulcer bleeding from stomach or small intestine could be a life-threatening condition. There are various endoscopic modalities of treatment to control bleeding, e.g. cautery, clip application, and epinephrine injection. Some ulcers are too deep and are at risk of perforation if extensive cauterization is performed. Clip application might be unsuccessful for ulcers that are too wide to close with a clip. Cyanoacrylate superglue spray may prove to be a new way to control bleeding from stomach ulcers that are difficult to treat with cautery or clip, and may help to avoid surgery or life-threatening events in such patients.

Read the abstract

Initial EGD Bleeding pyloric channel ulcer

Initial EGD Pyloric channel ulcer with adherent clot

Initial EGD adherent clot

Initial EGD sp Epinephrine injection

Initial EGD mechanical clot removal

Initial EGD bipolar electrocoagulation

Initial EGD sp control of bleeding

Repeat EGD bleeding from pyloric channel ulcer

Repeat EGD pyloric channel ulcer with fresh blood clot

Repeat EGD sp bipolar electrocoagulation

Repeat EGD unsuccessful clip application

Repeat EGD sp 5 cc of glue spray on right side of ulcer

Repeat EGD sp glue spray control of bleeding

Authors Contact Siddharth Javia, MD; Nirav C. Thosani, MD, MHA, University of Texas Health Science Center at Houston



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