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Oral 67 Incremental Yield of Dysplasia Detection in Barrett’s Esophagus Using Volumetric Laser Endomicroscopy With and Without Laser Marking Compared to a Standardized Random Biopsy Protocol
Author Insight from Mohammad Alshelleh, MD, Hofstra Northwell School of Medicine, Northwell Health System
What’s new and important here?
Esophageal cancer is on the rise despite knowing the precursor lesion, Barrett’s esophagus (BE).
This is likely due to problems in screening as well as detecting dysplasia in patients with known BE, as often dysplasia is focal and hard to find.
Volumetric laser endomicroscopy with laser marking (VLEL) is a new wide field advanced imaging technology for BE to help detect dysplasia. Until now no data exists on incremental yield of dysplasia detection by using VLEL.
Our results showed that VLEL led to statistically significant higher yield of dysplasia detection compared to a standard, random biopsy protocol in patients surveyed in academic centers.
These results support the use of VLELL for surveillance in BE in academic centers.
Mohammad Alshelleh, MD, Hofstra Northwell School of Medicine, Northwell Health System
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