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The American College of Gastroenterology offers Clinical Research Awards of up to $50,000 for original research in clinical gastroenterology and will consider applications for pilot projects up to $15,000 within this award category. At least one of the investigators must be an ACG member or trainee member at the time of submission of the grant proposal. Note that physicians in training (interns, residents, fellows) are eligible to apply provided that the work is conducted under the preceptorship of a more senior or experienced investigator. In order to assure diversity among recipients, no more than two Clinical Research Awards will be granted to former or current principal investigators on R01, P01, U01, VA Merit Awards or Hughes grants, or to those who hold the position of full professor at an academic institution. Awardees will be selected based on feasibility, scientific and clinical significance, originality and anticipated contribution of the research to clinical practice. Applications will also be evaluated on the availability of adequate resources, including personnel and facilities.

Description

The American College of Gastroenterology (ACG) is offering Clinical Research Awards of up to $50,000 for original clinical research. For these awards, preliminary data are expected. As part of the ACG Clinical Research Award, the College also supports pilot projects of up to $15,000 to encourage clinical research among trainees and junior faculty. Pilot awards do not require previous work or preliminary data, and do not cover randomized controlled trials. The number and size of awards will be determined by the ACG Research Committee.

Objective

The mission of the ACG Clinical Research Awards program is to fund innovative patient-oriented research. For the purposes of these awards, patient-oriented research is defined as: (1) Research conducted with human subjects, (2) Research on new diagnostic and therapeutic interventions, and (3) Research on material of human origin, such as tissues and specimens. While research that explores mechanisms of human disease is highly encouraged, the research projects should be translational in nature, with direct applicability to clinical care. In general, studies involving animals will not be considered unless the work cannot be done in humans.

Eligibility

At least one of the investigators must be an ACG member or trainee member at the time of submission of the grant proposal. If you are submitting an application for membership, all member applications must be submitted by September 27, 2019 in order to be eligible for review at the October Credentials Committee meeting, which is the last opportunity to be approved for full membership prior to the grant application deadline (note: Resident and Trainee applications are reviewed biweekly). To Join ACG, click here. For questions on ACG membership, please email: info@gi.org or call: 301-263-9000.

Note that physicians in training (interns, residents, fellows) are eligible to apply provided that the work is conducted under the preceptorship of a more senior or experienced investigator. In order to assure diversity among recipients, no more than two Clinical Research Awards will be granted to former or current principal investigators on R01, P01, U01, VA Merit Awards or Hughes grants, or to those who hold the position of full professor at an academic institution. Successful applicants must agree to acknowledge ACG support in any publications that result from the research, and to submit a final report to the ACG Research Committee within 18 months of receipt of funding.

Selection Criteria

In evaluating the merits of an application, the Committee will consider its scientific and clinical significance (25%), feasibility (including availability of adequate resources, such as personnel and facilities) (25%), and methods (50%). The methods component is comprised of the availability of preliminary data, if applicable (25%), the study design (50%), and power, sample size and statistical analysis (25%). If an individual submits more than one grant proposal, only one award can be made for a given Principal Investigator. If a given investigator submits both a pilot and a larger clinical research grant deemed worthy of funding, the larger grant will be funded. The same project should not be submitted for multiple grant types, and will not be considered if this occurs.

Review Process

The ACG Research Committee will review the grant proposals, using its standardized process.

Deadline

Submit the application through ACG’s online grant application system, which will open in September, by the DEADLINE: Friday, December 6, 2019. Applicants will be notified by April 1, 2020. The award period will begin July 1, 2020.


Application Overview

Applicants are required to submit a single Adobe PDF document comprising the complete grant submission. The single PDF document must be uploaded through the online application portal. This includes all required sections of the grant, in the order listed below. Format all pages with 1″ margins and a font no smaller than 11 point. Type your name (last name, first name) and the name of the award in the upper right hand corner of each page, and the page number in the upper left hand corner of each page. FAILURE TO ADHERE TO THESE INSTRUCTIONS WILL CAUSE THE GRANT APPLICATION TO BE RETURNED UNREVIEWED.

You will be required to provide the following information through ACG’s online grant system:


Application Components

  1. RE-SUBMISSIONS — For re-submissions, in addition to selecting “Yes” in the re-submission field of the online application, you must submit a cover letter responding to the reviewers critiques/outlining how you have updated your application. This should be included as the first section of your Research Proposal, as part of the PDF upload to the grant system. Limit 2 pages.
  2. RESEARCH PROPOSAL — Limit to 5 pages (excluding references and budget).
    • Specific Aims — Provide a clear description of the study objectives. Consider the following questions: What is the hypothesis to be addressed? What are the immediate objectives? What are the ultimate objectives? How does the proposed research fit into an overall research program?
    • Background/Significance — State how the proposed work bears on prior work and indicate how it will extend the boundaries of current knowledge.
    • Pilot Data/Previous Work — For larger grant proposals (defined as >$15,000) pilot data/previous work is expected. Pilot awards of ≤$15,000 do not require previous work or preliminary data. Be sure to select the appropriate grant type, from the pull down menu, in the online application system, specify “Clinical Research ‘Pilot Study’ Award ≤$15,000” for pilot grants.
    • Research Plan — Give the details of the research plan, including the inclusion/exclusion criteria for enrollment, methods to be used, the kinds of data that are to be collected, and how these data will be analyzed. Provide detailed sample size estimates. Grants without a statistical analysis section or sample size justification are unlikely to be successful.
    • References — Include a separate section for references (not included in page limit). Be judicious in the use of references.
    • Budget & Justification — Include a separate section for the budget (not included in page limit). This should include a budget table listing each expense for the grant period, followed by a budget justification, a written explanation of each expense and how it relates to the project. Indicate how the funds will be allocated and justify each budget item, including facility fees if funds are requested for this purpose. Note that salary support for the Principal Investigator and Co-Investigators will not be provided. Salary support will be provided for other personnel (research nurse, computer programmer) if adequately justified. Support will be provided for supplies and equipment. In general, major equipment acquisitions are not supported. Travel and manuscript preparation costs are not supported. Indirect costs (i.e., university overhead) are not provided. For pilot projects: If part of larger study, delineate how this grant support will be utilized vs. other funding.
  3. OTHER SUPPORT — For each investigator, list the title, funding agency, total direct costs, dates (including expected dates of notification) of all active awards and pending funding. Use NIH format. Indicate whether any scientific or budgetary overlap exists, and if so, indicate how this will be addressed.
  4. IRB APPROVAL LETTER — Include any available information (see above).
  5. CURRICULUM VITAE — Provide for each investigator. Use NIH format and adhere to the NIH 5-page limit. For sample format see the NIH webpage.
  6. SUPPORTING LETTERS — Provide letters from collaborators, such as those supplying patient referrals, if applicable. Applications in which a physician in training serves as Principal Investigator must be accompanied by a supporting letter from the individual’s program director.
  7. APPENDICES — Use (if needed) for data collection forms. Do not use to expand Research Proposal (Section B above).

Applications Must Be Submitted Electronically
DEADLINE: FRIDAY, DECEMBER 6, 2019
QUESTIONS: Phone: 301-263-9000 or email