Competency Questions for Managing IBD: Implementing IBD Evidence-Based Guidelines

1. When applying a weak (also known as conditional) recommendation in a guideline statement to your clinical practice, which of the following is the most accurate?

A. All weak recommendations should be enacted
B. All weak recommendations should be avoided
C. Weak recommendations should be approached using shared decision making
D. Weak recommendations mean that there is equivalent data, and either option can be implemented in practice

Incorrect.

The correct answer is: C. Weak recommendations should be approached using shared decision making.

Correct!

2. Which of the following types of studies would provide the highest level of evidence to a guideline recommendation?

A. Case control study
B. Retrospective cohort study
C. Randomized controlled trial
D. Prospective cohort study

Incorrect.

The correct answer is: C. Randomized controlled trial.

Correct!

3. Which of the following statements is most accurate in describing the efficacy of infliximab for the treatment of moderate to severe ulcerative colitis?

A. Infliximab should always be used as monotherapy
B. Infliximab should always be combined with methotrexate
C. Monotherapy with infliximab is just as effective as combination therapy with azathioprine
D. Infliximab combined with azathioprine is more effective than monotherapy

Incorrect.

The correct answer is: D. Infliximab combined with azathioprine is more effective than monotherapy.

Correct!

4. What are the main results of the only head to head study of biologic therapies for the treatment of ulcerative colitis for the outcome of clinical remission at 52 weeks?

A. Vedolizumab is more effective than adalimumab
B. Ustekinumab is more effective than vedolizumab
C. Infliximab is more effective than adalimumab
D. Golimumab is more effective than vedolizumab

Incorrect.

The correct answer is: A. Vedolizumab is more effective than adalimumab.

Correct!

5. When interpreting data from network meta-analyses for positioning of therapies in IBD, which of the following is most accurate:

A. Direct comparisons can be made across studies through this technique
B. Network meta-analyses always result in high level data for a guideline
C. Indirect comparisons are made between trials based on a common comparator
D. Differences between therapies are always clinically significant in these analyses

Incorrect.

The correct answer is: C. Indirect comparisons are made between trials based on a common comparator.

Correct!

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Competency Questions for Managing IBD: Implementing IBD Evidence-Based Guidelines Clinician Education Video Series from The American College of Gastroenterology and The Crohn’s & Colitis Foundation

Incorrect.

Correct!

Incorrect.

Correct!

Incorrect.

Correct!

Incorrect.

Correct!

Incorrect.

Correct!

Competency Questions for Managing IBD: Implementing IBD Evidence-Based Guidelines
Clinician Education Video Series from The American College of Gastroenterology and The Crohn’s & Colitis Foundation