For patients and providers trying to understand the benefits and risks of CRC screening via colonoscopy or FIT, the SCREESCO study provides valuable data we can share with our patients to help them make informed decisions. An important caveat in extrapolating the FIT data from this study to patients in the United States is to highlight that while the SCREESCO trial used a two-stool FIT protocol, we typically perform annual single-sample testing in the United States. 

I follow the USMSTF for CRC recommendations for post polypectomy which currently suggest a 5-year follow up for these patients. These data support that recommendation by demonstrating that the risk for these patients is elevated at second surveillance colonoscopy and is independent of known risk factors as well as the adenoma detection rates of the endoscopists performing the colonoscopies.

This study demonstrates a more dynamic process as being potentially successful and easily adoptable throughout the world. Namely, by having patients able to interact with an application at home prior to endoscopy they can alert offices to difficulty with preparation or only present to endoscopy suites when their preparation has completed.

Using data from examinations using all indications rather than screening exams alone can be beneficial by allowing a larger sample size, which may provide a more accurate assessment of an endoscopist’s overall performance. It can also mitigate potential gaming by endoscopists to manipulate their metrics.

EHR Templates Improve Colonoscopy Surveillance Accuracy Timothy Yen, MD Assistant Professor, Loma Linda University Health, Loma Linda, CA This article…

The term “advanced adenoma” carries an ominous connotation, as it signifies a high risk for colorectal cancer (CRC), causing concern for both patients and clinicians. Evidence, including data from the New Hampshire Colonoscopy Registry, supports this concern by showing that individuals with advanced adenomas face a higher risk of future advanced neoplasia—defined as the combined risk of CRC and other advanced adenomas—compared to those with non-advanced or no polyps.

This is the first study to assess the impact of exposure to AI CADe on colonoscopy quality and physician performance in the absence of AI assistance. One of the posited risks of AI tools has been a decline in human-only colonoscopy quality, and this study provides important, novel observational data on how these AI tools may potentially negatively impact physician performance.

This summary reviews the 2025 Lancet article on the effect of invitation to colonoscopy versus fFIT screening on colorectal cancer mortality. Is an invitation to colorectal cancer (CRC) screening using fecal immunochemical test (FIT) non-inferior to colonoscopy?

This summary reviews Anderson JC, Rex DK, Mackenzie TA, Hisey W, Robinson CM, Butterly LF. Adenoma detection rates calculated using all examinations are associated with lower risk for postcolonoscopy colorectal cancer: Data from the New Hampshire Colonoscopy Registry. Am J Gastroenterol. 2025. doi: 10.14309/ajg.0000000000003488.

High-quality colonoscopy is essential for evaluation of the colon, such as de-tecting and monitoring precancerous le-sions. Suboptimal bowel preparation decreases colonoscopy efficacy and is as-sociated with significant adenoma and advanced adenoma miss rates. This summary reviews the USMSTF recommendations on optimizing bowel preparation for colonoscopy.