The term “advanced adenoma” carries an ominous connotation, as it signifies a high risk for colorectal cancer (CRC), causing concern for both patients and clinicians. Evidence, including data from the New Hampshire Colonoscopy Registry, supports this concern by showing that individuals with advanced adenomas face a higher risk of future advanced neoplasia—defined as the combined risk of CRC and other advanced adenomas—compared to those with non-advanced or no polyps.

This is the first study to assess the impact of exposure to AI CADe on colonoscopy quality and physician performance in the absence of AI assistance. One of the posited risks of AI tools has been a decline in human-only colonoscopy quality, and this study provides important, novel observational data on how these AI tools may potentially negatively impact physician performance.

This summary reviews the 2025 Lancet article on the effect of invitation to colonoscopy versus fFIT screening on colorectal cancer mortality. Is an invitation to colorectal cancer (CRC) screening using fecal immunochemical test (FIT) non-inferior to colonoscopy?

This summary reviews Anderson JC, Rex DK, Mackenzie TA, Hisey W, Robinson CM, Butterly LF. Adenoma detection rates calculated using all examinations are associated with lower risk for postcolonoscopy colorectal cancer: Data from the New Hampshire Colonoscopy Registry. Am J Gastroenterol. 2025. doi: 10.14309/ajg.0000000000003488.

High-quality colonoscopy is essential for evaluation of the colon, such as de-tecting and monitoring precancerous le-sions. Suboptimal bowel preparation decreases colonoscopy efficacy and is as-sociated with significant adenoma and advanced adenoma miss rates. This summary reviews the USMSTF recommendations on optimizing bowel preparation for colonoscopy.

Optimal Colorectal Cancer Prevention With Stool Tests Depends on High Quality Colonoscopy Joseph C. Anderson, MD, FACG VA Medical Center,…

Cold Endoscopic Mucosal Resection of Polyps >10 mm Joseph C. Anderson, MD, FACG VA Medical Center, White River Junction, VT;…

Does Colonoscopy with Water Exchange Decrease Right Colon Polyp Miss Rates? Joseph C. Anderson, MD, FACG  VA Medical Center, White…

Hot Take: Can We Lengthen Surveillance Intervals After EMR With Margin Thermal Ablation? Margaret J. Zhou, MD, MS Clinical Assistant…

Cold vs Hot Snare Resection of Large Polyps:  A Cooler, Safer Approach for Large Colorectal Polyps Ahmad Abu-Heija, MBBS Consultant…