*EMBARGOED All research presented at the 2021 ACG Annual Scientific Meeting and Postgraduate Course is strictly embargoed until Sunday, October 24, 2021, at 3:30 pm EDT.

Joseph C. Anderson, MD, MHCDS, FACG
Joseph C. Anderson, MD, MHCDS, FACG

Oral 1 Mean Adenomas Per Colonoscopy Is Inversely Associated With Post Colonoscopy Colorectal Cancers: Data From the New Hampshire Colonoscopy Registry Validating This Quality Measure

Author Insight from Joseph C. Anderson, MD, MHCDS, FACG, White River Junction VA Medical Center

What’s new here and important for clinicians?

Adenomas per colonoscopy may be a better quality measure than adenoma detection rate since it reflects the ability of an endoscopist to optimize colorectal cancer prevention by clearing the colon of all precursors. One major limitation is that there are no data examining the association between APC and incidence of post colonoscopy CRC (PCCRC). Our data suggest that an APC of 0.6 (HR= 0.29) may offer more protection from PCCRC than 0.4 (HR=0.40) within first 3 years of an index exam. Thus, our data validate APC as a quality measure.

What do patients need to know?

Adenoma detection rate (ADR) is the number of screening exams performed by an endoscopist with at least one adenoma or important cancer precursor detected and removed. ADR is an important quality measure for endoscopists. Adenomas per colonoscopy (APC) measures the number of adenomas that an endoscopist finds on average during a colonoscopy. We found in our study that endoscopists with a higher APC had lower rates of post colonoscopy CRC. Thus, the number of adenomas detected (as opposed to at least one as measured in the ADR) may be an important measure of an endoscopist’s ability to prevent CRC in patients having colonoscopy by that physician.

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Author Contact
Joseph C. Anderson, MD, MHCDS, FACG, White River Junction VA Medical Center
joseph [dot] anderson [at] dartmouth [dot] edu

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