*EMBARGOED All research presented at the 2020 ACG Annual Scientific Meeting and Postgraduate Course is strictly embargoed until Monday, October 26, 2020, at 8:00 am EDT.

Mohamed Tausif Siddiqui, MD
Mohamed Tausif Siddiqui, MD

Oral 10 Tunneled Intravenous Catheters for Home Parenteral Nutrition Have a Lower Rate of Deep Vein Thrombosis Than PICC Lines in Inflammatory Bowel Disease

Author Insight from Mohamed Tausif Siddiqui, MD, Cleveland Clinic Foundation

What’s new here and important for clinicians?

Patients with Inflammatory Bowel Disease (IBD) are at a higher risk of thrombosis. These patients also have a higher risk of malnutrition and often require short- or long-term intravenous nutrition support. Central venous access catheters for infusion of parenteral nutrition can cause further increase in thrombosis risk.

We conducted a retrospective analysis of the patients with IBD who received home parenteral nutrition (PN) and noted higher rates of catheter-associated deep vein thrombosis (DVT) in patients with Peripherally Inserted Central catheters (PICC) compared to the tunneled catheters with a significantly high odds ratio (OR) of 3.66, p<0.05 and a respective DVT rate of 0.16 vs 0.08 per 1,000 catheter days.

These findings are important for the physicians caring for patients with IBD, gastroenterologists specializing in nutrition, and the clinical nutrition support teams. Our study can help these clinicians in strategically planning an appropriate access to minimize the potential complications that these patients commonly experience while receiving home PN. Our research also validates our long-term practice of suggesting tunneled central lines for the IBD patients receiving Home Parenteral Nutrition.

What do patients need to know?

  • Patients with Crohn’s Disease and Ulcerative Colitis are at a higher risk of developing blood clots (thrombosis).
  • Ask your doctors about the different types of intravenous catheter options which are available for long term intravenous infusions such as parenteral nutrition.
  • In general, we recommend tunneled catheters over PICC line for long term parenteral nutrition infusion because it has shown to be associated with lower risk of thrombosis.
  • Discuss with your gastroenterologist or the primary care provider to pick an intravenous access catheter that may be the best fit for your clinical situation, and which has minimal risk of complications.

    Read the Abstract

    Author Contact
    Mohamed Tausif Siddiqui, MD, Cleveland Clinic Foundation
    dr_tausifsiddiqui [at] yahoo [dot] com

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