*EMBARGOED All research presented at the 2021 ACG Annual Scientific Meeting and Postgraduate Course is strictly embargoed until Sunday, October 24, 2021, at 3:30 pm EDT.

Seth A. Gross, MD, FACG
Seth A. Gross, MD, FACG

Oral 2 Prospective Randomized Trial Comparing Endocuff™-Assisted Colonoscopy vs. G-EYE™ Balloon-Assisted Colonoscopy: A Multicenter Study

Author Insight from Seth A. Gross, MD, FACG, NYU Langone Health

What’s new here and important for clinicians?

Colonoscopy is the gold standard for colorectal cancer screening and surveillance, but folds and blind spots within the colon can harbor pre-cancerous polyps (adenomas) that may be easily missed by skilled endoscopists. To bridge the gap of missed adenomas, various technologies were developed to increase adenoma detection, including products for mechanical manipulation of colonic folds and optical technologies allowing rear-view of adenomas in the proximal aspects of folds. Recent studies and meta-analyses suggest that mechanical manipulation is superior to optical techniques in detection enhancement. This study is the first head-to-head randomized trial between two mechanical enhancement methods – the G-EYE™ balloon and Endocuff Vision (ECV) attachment. The data presented at ACG 2021 demonstrate that the G-EYE™ balloon increased adenoma detection compared with the Endocuff Vision™ (ECV) colonoscope attachment, mostly large and advanced adenomas. Increasing the detection of adenomas during colonoscopy will prevent the development of colon cancer and improving patient outcomes. In my experience using G-EYE™, which has recently became available in the USA, the technology has a short learning curve and can provide endoscopists with better visualization, stabilization and control during routine examinations.

What do patients need to know?

In the United States, CRC is the second leading cause of cancer-related deaths. Detection and removal of adenomas in colonoscopy can prevent the development of colorectal cancer. While colonoscopy is the gold standard for detection and removal of adenomas, polyps can be hard to see and can missed during the procedure due to the anatomy of the colon. G-EYE™ is proven through clinical and real-world studies to increase adenoma detection rate compared to standard colonoscopy. This study shows that the G-EYE™ technology is proven to reduce miss rates of adenomas, which in turn can reduce the incidence of interval colon cancer.

Read the Abstract

Author Contact
Seth A. Gross, MD, FACG, NYU Langone Health
seth [dot] gross [at] nyulangone [dot] org

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