*EMBARGOED All research presented at the 2023 ACG Annual Scientific Meeting and Postgraduate Course is strictly embargoed until Sunday, October 22, 2023, at 3:00 pm PT.

Oral 36 – Monitoring IBD by Intestinal Ultrasound Decreases Time to Treatment Change and Time to Remission in Comparison to Conventional Management
Tuesday, October 24, 2023 | 9:50 AM – 10:00 AM PT | Location: Ballroom B

Author Insight from Noa Krugliak Cleveland, MD, University of Chicago Medicine, Inflammatory Bowel Disease Center

What’s new here and important for clinicians?

In our study we prospectively followed patients with ulcerative colitis or Crohn’s disease who were receiving upadacitinib therapy and evaluated whether those who were followed by intestinal ultrasound to assess response to therapy had earlier adjustment to therapy and whether they achieved remission sooner than those who were followed by conventional management (clinic visits, blood work, colonoscopy, CT, or MR).

We found that patients who were evaluated by intestinal ultrasound had their therapy adjusted within on average one day compared to 17 days in the conventional management group.

We also found that the average time to achieving remission in the group followed by intestinal ultrasound was shorter, on average 27 days, compared to 55 days in the conventional group.

What do patients need to know?
Intestinal ultrasound is a point-of-care (bedside), non-invasive, highly accurate tool to assess disease activity and response to therapy in both Crohn’s disease and ulcerative colitis. This study demonstrates that using intestinal ultrasound to monitor a patient’s response to therapy leads to quicker adjustment to therapy and significantly shorter time to achieving symptomatic remission.

Read the Abstract

Active inflammation of the small intestine featuring increased bowel wall thickness and blood flow characterized by color Doppler

Author Contact
Noa Krugliak Cleveland, MD, University of Chicago Medicine, Inflammatory Bowel Disease Center

noa.cleveland [at] uchospitals.edu

Media Interview Requests
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