*EMBARGOED All research presented at the 2021 ACG Annual Scientific Meeting and Postgraduate Course is strictly embargoed until Sunday, October 24, 2021, at 3:30 pm EDT.

Srinivas Gaddam, MD, MPH
Srinivas Gaddam, MD, MPH

P0009 Concerning Trend in Increasing Pancreatic Cancer (PC) Incidence Among Young Women: A Population-Based Time-Trend Analysis Using the Surveillance, Epidemiology, and End Results (SEER) Database

Author Insight from Srinivas Gaddam, MD, MPH, Cedars-Sinai Medical Center

What’s new here and important for clinicians?

Population-based data shows that pancreatic cancer incidence rates have been increasing in both men and women over the past two decades. The incidence of pancreatic cancer is more common in men than women; and is steadily increasing in both sexes at a similar rate. When we looked specifically at younger women less than 50 years of age, it was found that there is a disproportionate trend of increasing pancreatic cancer in women when compared to men. This rise was especially more pronounced in women aged 15-34. If the current trend persists, pancreatic cancer incidence rate in women aged 15-34 is estimated to be 400% that of their counterpart men by 2040. Future studies should validate these findings in other databases.

What do patients need to know?

Pancreatic cancer incidence rates have been increasing in the US during 2000-2018. Previous studies have shown that men are at higher risk of pancreatic cancer than women. Our study shows that it is rising more rapidly in young women below the age of 50 when compared to young men. However, the overall incidence of this cancer continues to be very low in young individuals despite this reversal of trend.

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Author Contact
Srinivas Gaddam, MD, MPH, Cedars-Sinai Medical Center
srivinas [dot] gaddam [at] cshs [dot] org

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