The American Journal of Gastroenterology Author Podcasts

Each month the Co-Editors-in-Chief of The American Journal of Gastroenterology, Dr. William Chey and Dr. Paul Moayyedi, select a topic from the table of contents to highlight important clinical science for practicing gastrointestinal specialists.

March 2014

Comparing Trends in Esophageal Adenocarcinoma Incidence and Lifestyle Factors Between the United States, Spain, and The Netherlands — A Podcast with Nicholas J. Shaheen, MD, MPH, FACG

Nicholas J. Shaheen, MD, MPH, FACG, author of an editorial on a recent article on esophageal adenocarcinoma trends across three nations published in the March 2014 issue of AJG, talks with AJG Co-Editor Dr. William Chey about the rising incidence of esophageal adenocarcinoma, the most important and interesting conclusions drawn from this ecological study, and the role that GERD, Barrett’s esophagus, tobacco smoking, alcohol consumption, and obesity all play in the pathogenesis of this disease. (22:25)

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Click here to read the article. Click here to read the editorial.

February 2014

The Impact of Physical Complaints, Social Environment, and Psychological Functioning on IBS Patients’ Health Perceptions: Looking Beyond GI Symptom Severity — A Podcast with Jeffrey M. Lackner, PsyD

Jeffrey M. Lackner, PsyD, co-author of new research on the correlation between self-ratings of health and IBS symptom severity published in the February 2014 issue of AJG, talks with AJG Co-Editor Dr. Paul Moayyedi about how fatigue, somatization, and negative social interactions might serve as key predictors for self-rated health in IBS, how IBS symptom severity has a surprisingly modest role in self-rated health, and how doctors can better consider the psychological experience of IBS and how that impacts treatment and patient response. (22:31)

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Click here to read the article.

January 2014

Differential Effects of FODMAPs (Fermentable Oligo-, Di-, Mono-Saccharides and Polyols) on Small and Large Intestinal Contents in Healthy Subjects Shown by MRI — A Podcast with Robin C. Spiller, MD, FRCP

Robin C. Spiller, MD, FRCP, co-author of new research on the effect of FODMAPs such as fructose and fructans on irritable bowel syndrome (IBS) symptoms published in the January 2014 issue of AJG, talks with AJG Co-Editor Dr. William D. Chey about the dietary substances included in the FODMAP classification, the MRI imaging techniques used to measure FODMAP impact on colonic distention and gas production in this study, and how clinicians might consider FODMAPs along with gluten and lactose when recommending dietary interventions for IBS patients. (21:53)

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Click here to read the article.

December 2013

Clinical and Endoscopic Characteristics Do Not Reliably Differentiate PPI-Responsive Esophageal Eosinophilia and Eosinophilic Esophagitis in Patients Undergoing Upper Endoscopy: A Prospective Cohort Study – A Podcast with Evan S. Dellon, MD, MPH

Evan S. Dellon, MD, MPH, co-author of new research on the distinguishing features of PPI-responsive esophageal eosinophilia and eosinophilic esophagitis (EoE) published in the December issue of AJG, talks with AJG Co-Editor Dr. Paul Moayyedi about the clinical features evaluated in the study, the lack of significant distinguishing association of these features to either disease, the role of PPIs in reducing eosinophils, and potential future studies worthy of pursuit in this area. (20:05)

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Click here to read the article.

November 2013

Patient Assessments and Online Ratings of Quality Care: A “Wake-Up Call” for Providers – A Podcast with David A. Johnson, MD, FACG

David A. Johnson, MD, FACG, co-author of new research on the emerging impact of online patient evaluation websites (PEWs) published in the Red Section of the November issue of AJG, talks with AJG Co-Editor William D. Chey, MD, FACG, about the rating metrics used by these websites, the characteristics of typical users, and the potential ways in which physicians can interact with these sites to improve doctor-patient communication and manage their online reputation. (18:34)

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Click here to read the article.

October 2013

Temporal Bacterial Community Dynamics Vary Among Ulcerative Colitis Patients After Fecal Microbiota Transplantation – A Podcast with Sieglinde Angelberger, MD, and David Berry, PhD

Sieglinde Angelberger, MD, and David Berry, PhD, co-authors of new research on the efficacy of fecal microbiota transplantation (FMT) in patients with ulcerative colitis published in the October issue of AJG, talk with AJG Co-Editor Dr. Paul Moayyedi about the highlights of their case series, including choice of stool donors, route and duration of administration, impact of FMT on these patients’ gut microbiota, and what the disappointing response to FMT in these ulcerative colitis cases suggests for further research into this practice. (16:20)

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Click here to read the article.

September 2013

New Practice Guidelines on Acute Pancreatitis – A Podcast with Scott M. Tenner, MD, MPH, FACG

Scott M. Tenner, MD, MPH, FACG, co-author of the American College of Gastroenterology’s new Clinical Guideline on the Management of Acute Pancreatitis, published in the September issue of AJG, talks with Co-Editor Dr. William Chey about the increasing prevalence of acute pancreatitis; the appropriateness of CT, MR, ERCP, and genetic testing in diagnosis of the disease; and the role of antibiotics, re-feeding, surgical debridement, and lactated ringer’s solution versus normal saline in the management of acute pancreatitis. (24:54)

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Click here to read the article.

August 2013

New Practice Guidelines on Achalasia – A Podcast with Michael F. Vaezi, MD, FACG, John E. Pandolfino, MD, and Marcelo F. Vela, MD

Michael F. Vaezi, MD, FACG, John E. Pandolfino, MD, and Marcelo F. Vela, MD, co-authors of the American College of Gastroenterology’s new Clinical Guideline on the Diagnosis and Management of Achalasia published in the August issue of AJG, talk with Co-Editor Dr. Paul Moayyedi about the incidence, prevalence, and diagnosis of this disorder; the best treatment options—including myotomy, pneumatic dilatation, and botulinum toxin—according to achalasia subtype and patient age, gender, and preference; as well as the long-term outlook and risks for achalasia patients after successful therapy. (25:58)

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Click here to read the article.

July 2013

The Acid Pocket: A Target for Treatment in Reflux Disease?
A Podcast with Peter J. Kahrilas, MD, FACG
Peter J. Kahrilas, MD, FACG, co-author of new research published in the July issue of AJG about the “acid pocket,” an area of unbuffered gastric acid that accumulates in the proximal stomach after meals, talks with AJG Co-Editor William D. Chey, MD, FACG, about the definition and genesis of the acid pocket concept; the relationship between this phenomenon and hiatal hernia, erosive esophagitis, and Barrett’s esophagus; as well as evolving methods to identify and target the acid pocket for the treatment of GERD. (21:50)Click here to listen to the podcast. Download from iTunesClick here to read the article.

June 2013

High Economic Burden of Caring for Patients with Suspected Extraesophageal Reflux – A Podcast with Michael F. Vaezi, MD, FACG, and David O. Francis, MD

Michael F. Vaezi, MD, FACG, and David O. Francis, MD, co-authors of new research on the high costs of caring for patients with extraesophageal reflux symptoms published in the June issue of AJG, talk with AJG Co-Editor Dr. Paul Moayyedi about the prevalence of various extraesophageal reflux symptoms, the costs of treating these symptoms, the impact of tertiary care centers in both patient improvement and health care costs, and whether the best treatment for extraesophageal reflux is perhaps no treatment at all. (26:44)

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Click here to read the article.

May 2013

New Practice Guidelines on the Diagnosis and Management of Celiac Disease – A Podcast with Joseph A. Murray, MD, FACG, and Ciarán P. Kelly, MD, FACG

Joseph A. Murray, MD, FACG, and Ciarán P. Kelly, MD, FACG, co-authors of the American College of Gastroenterology’s new Clinical Guideline on the Diagnosis and Management of Celiac Disease, talk with AJG Co-Editor William D. Chey, MD, FACG, about the key components of the guidelines, including the working definition of celiac disease, screening techniques such as small bowel biopsy and genetic testing, best practices for gluten challenge, as well as routine celiac patient monitoring and emerging treatments. (35:42)

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Click here to read the guideline.

New Practice Guidelines on Esophageal Eosinophilia and Eosinophilic Esophagitis (EoE) – A Podcast with David A. Katzka, MD, FACG

David A. Katzka, MD, FACG, co-author of the American College of Gastroenterology’s new Clinical Guideline on the Diagnosis and Management of Esophageal Eosinophilia and Eosinophilic Esophagitis (EoE), talks with AJG Co-Editor Dr. Paul Moayyedi about the key components of the guidelines, including the epidemiology of the disease, the difficulty of diagnosis for EoE, the role of diet and pharmacological therapy for treatment of EoE, and the urgent need for more research into this disease. (40:38)

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Click here to read the guideline.

Nuevas Guías de Práctica sobre el Diagnóstico y Manejo de la Enfermedad Celíaca – Un Podcast con Alberto Rubio-Tapia, MD

Alberto Rubio-Tapia, MD, co-autor de la American College of Gastroenterology Guía Clínica por el Diagnóstico y Manejo de la Enfermedad Celíaca, discute los elementos clave de las directrices con Editor Asociado Max Schmulson, MD. (28:00)

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Haga clic aquí para leer la guía.

April 2013

New Practice Guidelines on Clostridium difficile Infections –
A Podcast with Christina M. Surawicz, MD, MACG
Christina M. Surawicz, MD, MACG, co-author of the American College of Gastroenterology’s new Guidelines for the Diagnosis, Treatment, and Prevention of Clostridium difficile Infections, talks with AJG Co-Editor William D. Chey, MD, FACG, about the key components of the guidelines, including the epidemiology of the disease, the criteria for diagnosis of severe C. difficile infection, and appropriate treatment regimens for both mild-to-moderate and severe disease, including fecal transplantation. (14:10)Click here to listen to the podcast. Download from iTunesClick here to read the guideline.

March 2013

Expert Author Insight: New Practice Guidelines on GERD – A Podcast with Philip O. Katz, MD, FACG and Lauren B. Gerson, MD, MSc, FACG

Philip O. Katz, MD, FACG and Lauren B. Gerson, MD, MSc, FACG, two authors of the American College of Gastroenterology’s new Practice Guidelines for the Diagnosis and Management of Gastroesophageal Reflux Disease (GERD), talk with AJG Co-Editor Paul Moayyedi, MD, FACG, about the key components of the guidelines, including the prevalence of GERD, the recommendations for the approach to diagnosis and management, and the potential adverse events associated with PPI therapy. (33:33)

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Click here to read the guideline.

February 2013

The Role of Fecal Microbiota Transplant (FMT) in Treating C. difficile – A Podcast with Lawrence J. Brandt, MD, MACG

The American Journal of Gastroenterology (AJG) Co-Editor William D. Chey, MD, FACG, talks with Lawrence J. Brandt, MD, MACG, on the efficacy of this potentially lifesaving procedure and how the FDA’s recent classification of stool as a “drug” could impact physicians who want to use FMT as a treatment option for their patients. A leading pioneer in the use of fecal microbiota transplantation (FMT) in treating C. difficile infection, Dr. Brandt gave the 2012 AJG Lecture that was also published in the February issue. (33:10)

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Click here to read the article.

January 2013

Clinical Guideline: Management of Gastroparesis

The American Journal of Gastroenterology (AJG) Co-Editor Paul Moayyedi, MD, FACG, talks with Henry P. Parkman, MD, FACG, of Temple University, one of the lead authors of a new clinical guideline for the management of gastroparesis. Published in the January issue of AJG, the guideline addresses the definition, diagnosis, differential diagnosis, and treatment of gastroparesis, including nutritional supplementation, glycemic control, pharmacological, endoscopic, device, and surgical therapy. Dr. Parkman provides insight on the guideline’s key recommendations, including the scientifically-based evidence behind them. (25:43)

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Click here to read the article.

December 2012

Non-Celiac Wheat Sensitivity: Distinct Clinical Condition? – A Podcast with William D. Chey, MD, FACG, and Joseph A. Murray, MD

Recent research by Antonio Carroccio, MD, that suggests the existence of non-celiac wheat sensitivity as a distinct clinical condition is the basis for a discussion between AJG Co-Editor William D. Chey, MD, FACG, and Joseph A. Murray, MD, who is lead author of an upcoming clinical management guideline for celiac disease that will be published in the Red Journal. Dr. Murray helps define non-celiac gluten sensitivity, explores why gluten-free diets are unsatisfactory as a diagnostic tool, and explains the need for scientific advancement in this area. Dr. Carroccio’s paper was published in the December issue of The American Journal of Gastroenterology. (37:17)

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Click here to read the article.

November 2012

Linaclotide for Irritable Bowel Syndrome – A Podcast with William D. Chey, MD, FACG, and Satish Rao, MD, PhD, FACG

AJG Co-Editor Dr. Paul Moayyedi talks with William D. Chey, MD, FACG and Satish Rao, MD, PhD, FACG about two randomized controlled trials on linaclotide in irritable bowel syndrome (IBS) published in the December issue of The American Journal of Gastroenterology. The phase 3 trials report that this new therapy significantly reduces constipation and abdominal pain associated with some kinds of IBS. (35:31)

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Read the studies here and here.

October 2012

The Prevalence of Irritable Bowel Syndrome Symptoms in Inflammatory Bowel Disease

AJG Co-Editor Paul Moayyedi, MD, FACG, talks with Alexander C. Ford, MD, and Eamonn M. M. Quigley, MD, FACG, about the findings from the first systematic review of the literature of irritable bowel syndrome symptoms in inflammatory bowel disease. In the review, Dr. Ford and his co-investigator Stephen J. Halpin, MD, demonstrated that prevalence of symptoms compatible with IBS in patients with IBD is as high as 40%. This article and Dr. Quigley’s editorial “Irritable Bowel Symptoms in IBD: Diagnostic Uncertainty Meets Pathological Reality” were published in the October issue of the AJG. (23:08)

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Click here to read the article.

September 2012

New Meta-Analysis Shows No Protective Effect of 5-ASA Against CRC in IBD

Findings from a new meta-analysis focusing on non-referral studies suggest that 5-Aminosalicylic Acid offers little, if any, protection against colorectal cancer in Inflammatory Bowel Disease. In a conversation with AJG Co-Editor Dr. Paul Moayyedi, co-investigators Geoffrey C. Nguyen, MD, PhD, FRCPC and Charles N. Bernstein, MD explain why their findings conflict with previous clinic-based population studies and why 5-ASA should not be prescribed to IBD patients solely for their putative effects against CRC. (32:30)

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Click here to read the article.

August 2012

Gut Microbes: Role In GI Health & Disease with Mark Pimentel, MD

The importance of gut microflora in digestive health and disease is the topic of a July 2012 AJG Supplement. A podcast with Guest Editor Mark Pimentel, MD in conversation with Dr. Bill Chey covers post-infectious functional GI conditions, SIBO, IBS, and the role of methanogens, as well as an interesting perspective on probiotics in treating GI diseases. (20:36)

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Click here to read the article.

July 2012

Evidence Shows Higher Risk of C. diff Infection with PPIs – A Podcast with Yoon K. Loke, MD, MBBE

Findings from a new meta-analysis portray a cautionary tale on the use of PPI therapy in patients at significant risk of C. difficile infection. In conversation with AJG Co-Editor, Dr. William D. Chey, MD, Dr. Yoon K. Loke discusses his latest research findings that suggest concurrent use of antibiotics with PPIs increases the risk of CDI; and a lower risk of CDI with use of H2RAs. (17:00)

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Click here to read the article.

June 2012

Endotherapy for Barrett’s Esophagus – A Podcast with Irving Waxman, MD, FACG

Endotherapy for Barrett’s esophagus is the featured topic of the June 2012 Author Podcast featuring Dr. Irving Waxman of the University of Chicago. In conversation with Co-Editor of AJG, Dr. Paul Moayyedi, Dr. Waxman reviews Barrett’s surveillance and management strategies for patients with high grade dysplasia including a discussion of EMR and various ablative modalities. (27:10)

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Click here to read the article.

May 2012

Food Choice as a Key Management Strategy for Functional Gut Symptoms

Professor Peter Gibson reviews the quality of the evidence on diets high or low in poorly absorbed short-chain carbohydrates, known as FODMAPs (Fermentable Oligo-, Di- and Mono-saccharides and Polyols) and their impact on functional gastrointestinal symptoms. In a discussion with Co-Editor Dr. Bill Chey, Professor Gibson provides insights on implementing dietary approaches in the office and discusses the challenges of recognizing patients with non-celiac gluten sensitivity. (28:10)

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Click here to read the article.

April 2012

PPIs vs. H2RAs for Preventing GI Bleeding in Critically Ill Patients

Dr. Alan Barkun from McGill in Montreal, Canada is the author of a new systematic review and meta-analysis on PPIs vs. H2-receptor antagonists for stress related mucosal bleeding prophylaxis in critically ill patients. In a conversation with Dr. Paul Moayyedi, Professor Barkun reviews the evidence on the efficacy of PPIs vs. H2RAs in recurrent GI bleeding, ICU stay, mortality, and nosocomial pneumonia. (23:06)

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Click here to read the article.

March 2012

A conversation with Loren A. Laine, MD, FACG hosted by Dr. Chey on ACG’s new practice guideline, “Management of Patients with Ulcer Bleeding.”

Click here to listen to the Podcast (18:16). Download from iTunes

Click here to read the article.