Poster 1006 Breath Testing for Small Intestinal Bacterial Overgrowth in Irritable Bowel Syndrome: A Meta-analysis
Author Insight from Jonathan Pourmorady, MD, Cedars-Sinai Medical Center
What’s new here and important for clinicians?
Our meta-analysis of 1,641 patients in nine case-control studies revealed that positive hydrogen breath tests are more common among irritable bowel syndrome (IBS) patients in comparison to healthy controls, suggesting that small intestinal bacterial overgrowth (SIBO) is more common in the IBS patient population.
What do patients need to know?
The pathogenesis of IBS is multifactorial with various host factors contributing to the underlying disease process. More recently, there has been mounting evidence that the gastrointestinal microbiome and bacterial imbalance play an important role in the development of IBS. Breath testing is a mainstay clinical tool commonly used to diagnose SIBO, and our study revealed that positive breath tests were more prevalent in the IBS patient population compared to healthy controls.
Author Contact Jonathan Pourmorady, MD, Cedars-Sinai Medical Center
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