Poster 103 A Dual Center, Randomized Trial Comparing Colonoscopy and Oral Capsule Delivered Fecal Microbiota Transplantation in the Treatment of Recurrent Clostridium Difficile Infection: Preliminary Results
Author Insight from Dina Kao, MD, University of Alberta
What’s new here and important for clinicians?
The optimal route of delivering fecal transplant for recurrent Clostridium difficile infection (RCDI) has not been determined. Our preliminary results in this head-to-head study comparing colonoscopy vs pill delivery of fecal transplant seems to show that both ways are equally effective, approaching 100% in our study of patients who have mild to moderate RCDI.
What do patients need to know?
Both methods of delivery have pros and cons. In our study, patients have to take quite a number of pills, which would not be possible if individuals have swallowing difficulties. Pills have the advantage of being cheaper and not invasive. Colonoscopy is more invasive, but at the same time could also identify unexpected findings, such as polyps (growths in the large intestine).
Dina Kao, MD, University of Alberta
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