Patients find long-term use of proton pump inhibitors to reduce acid reflux can lead to other health problems, such as anemia, and the drugs can interact with other medications. Experts say taking PPIs can treat acid reflux symptoms, but often the underlying cause of the reflux, such as obesity and dietary indiscretion, is not addressed. Additionally, many patients find it difficult to stop taking the drugs. The New York Times (tiered subscription model)/Well blog
