Evidence-Based GI
Mirikizumab Is Effective for Induction and Maintenance of Ulcerative Colitis Rahul Dalal, MD, MPH Instructor, Division of Gastroenterology, Hepatology, and…
Is Early Ileo-cecal Resection for Crohn’s Disease an Appropriate Primary Treatment? Bharati Kochar, MD, MS Assistant Professor of Medicine,…
Which Endoscopists Benefit from Using Computer-Aided Detection of Polyps During Colonoscopy? Philip Schoenfeld, MD, MSEd, MSc (Epi) Chief (Emeritus),…
Post-Colonoscopy Colorectal Cancer Due to Missed Polyps in Proximal Colon or Rectum with Sub-Optimal Bowel Cleansing Jeffrey Lee, MD, MPH…
Dr Philip Okafor looks at a NEJM article on use of thalidomide for GI bleeding due to small intestinal angiodysplasia.
Editor-in-Chief Dr Philip Schoenfeld looks at a Phase 3 trial published in Lancet of 463 patients with IBS treated with tri-cyclic antidepressant and the effect on a patient’s IBS-Symptom Severity Score.
Drs Ashwini Arvind and Nicole E. Rich look at the decade-long, NIH-funded HEDS study for incidence and risk factors for hepatocellular carcinoma in cirrhosis.
In case you missed it! Dr Patel reviews a 2020 RCT published in Lancet that showed use of aspirin in patients with Lynch Syndrome reduced the long-term risk of developing CRC.
Multiple treatments for ulcerative colitis are now available. We look at a study published detailing a multi-center, double-blind, placebo-controlled RCT on etrasimod.
The goal of surveillance is to identify low-grade or high-grade dysplasia or early cancer at a treatable stage, however, current early cancer detection practices are ineffective. One potential explanation for these limitations is PEEC/PEEN, similar to the concept of post-colonoscopy colorectal cancer and related to endoscopy quality.