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Gi.org / Colon

Evidence-Based GI

EBGI Category: Colon


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  • Does prophylactic clipping prevent delayed bleeding after EMR of large proximal colonic polyps?

    American College of Gastroenterology / EBGI Articles / Colon / Does prophylactic clipping prevent delayed bleeding after EMR of large proximal colonic polyps?

    In this multicenter RCT of 356 patients across 19 hospitals, prophylactic clipping after EMR of large (≥20 mm) proximal colon polyps did not reduce delayed bleeding (9.0% vs. 6.1%, P = 0.30).

  • Artificial intelligence in colonoscopy: Could it be making us worse?

    American College of Gastroenterology / EBGI Articles / Colon / Artificial intelligence in colonoscopy: Could it be making us worse?

    This is the first study to assess the impact of exposure to AI CADe on colonoscopy quality and physician performance in the absence of AI assistance. One of the posited risks of AI tools has been a decline in human-only colonoscopy quality, and this study provides important, novel observational data on how these AI tools may potentially negatively impact physician performance.

  • COLONPREV trial of FIT vs colonoscopy

    American College of Gastroenterology / EBGI Articles / Colon / COLONPREV trial of FIT vs colonoscopy

    This summary reviews the 2025 Lancet article on the effect of invitation to colonoscopy versus fFIT screening on colorectal cancer mortality. Is an invitation to colorectal cancer (CRC) screening using fecal immunochemical test (FIT) non-inferior to colonoscopy?

  • All exam ADR performs similarly to screening ADR in predicting post colonoscopy colorectal cancer

    American College of Gastroenterology / EBGI Articles / Colon / All exam ADR performs similarly to screening ADR in predicting post colonoscopy colorectal cancer

    This summary reviews Anderson JC, Rex DK, Mackenzie TA, Hisey W, Robinson CM, Butterly LF. Adenoma detection rates calculated using all examinations are associated with lower risk for postcolonoscopy colorectal cancer: Data from the New Hampshire Colonoscopy Registry. Am J Gastroenterol. 2025. doi: 10.14309/ajg.0000000000003488.

  • Cold EMR for large colon polyps

    American College of Gastroenterology / EBGI Articles / Colon / Cold EMR for large colon polyps

    This summary reviews Pohl H, Rex DK, Barber J, et al. Cold snare endoscopic resection for large colon polyps: A randomised trial. Gut Published Online First: 19 May 2025. doi: 10.1136/gutjnl-2025-335075.

  • Can We Avoid Colonoscopies in Lynch Syndrome?

    American College of Gastroenterology / EBGI Articles / Colon / Can We Avoid Colonoscopies in Lynch Syndrome?

    Can non-invasive fecal immunochemical tests be used to extend surveillance intervals for colonoscopy among Lynch syndrome patients?

  • Tulisokibart: A New Drug for Moderate-to-Severe UC That May Come With Personalized Medicine

    American College of Gastroenterology / EBGI Articles / Colon / Tulisokibart: A New Drug for Moderate-to-Severe UC That May Come With Personalized Medicine

    Tulisokibart: A New Drug for Moderate-to-Severe UC That May Come With Personalized Medicine Ellen Axenfeld, MD1 and Elie S. Al…

  • Underwater EMR for Medium Sized Colorectal Sessile Polyps

    American College of Gastroenterology / EBGI Articles / Colon / Underwater EMR for Medium Sized Colorectal Sessile Polyps

    Underwater EMR for Medium Sized Colorectal Sessile Polyps Mohammad Bilal, MD, FACG  Associate Professor of Medicine, University of Colorado Anschutz…

  • Cold Endoscopic Mucosal Resection of Polyps >10 mm

    American College of Gastroenterology / EBGI Articles / Colon / Cold Endoscopic Mucosal Resection of Polyps >10 mm

    Cold Endoscopic Mucosal Resection of Polyps >10 mm Joseph C. Anderson, MD, FACG VA Medical Center, White River Junction, VT;…

  • Does Colonoscopy with Water Exchange Decrease Right Colon Polyp Miss Rates?

    American College of Gastroenterology / EBGI Articles / Colon / Does Colonoscopy with Water Exchange Decrease Right Colon Polyp Miss Rates?

    Does Colonoscopy with Water Exchange Decrease Right Colon Polyp Miss Rates? Joseph C. Anderson, MD, FACG  VA Medical Center, White…

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