Evidence-Based GI
This summary reviews Anderson JC, Rex DK, Mackenzie TA, Hisey W, Robinson CM, Butterly LF. Adenoma detection rates calculated using all examinations are associated with lower risk for postcolonoscopy colorectal cancer: Data from the New Hampshire Colonoscopy Registry. Am J Gastroenterol. 2025. doi: 10.14309/ajg.0000000000003488.
This summary reviews Pohl H, Rex DK, Barber J, et al. Cold snare endoscopic resection for large colon polyps: A randomised trial. Gut Published Online First: 19 May 2025. doi: 10.1136/gutjnl-2025-335075.
Bridging the Gap: Impact of Gender-Affirming Care on IBD Flare Rates Hayley Rogers, MD1 and Nikki Duong, MD2 1Advanced Endoscopy…
ELP is a rare and under-recognized condition that presents significant diagnostic and therapeutic challenges, especially for gastroenterologists who often encounter these patients first. There is no consensus on diagnostic criteria or standard treatment, and existing histologic scoring systems are often impractical for routine use due to variability and nonspecific findings. This study introduces a visually based severity score (ELPSS) tailored for endoscopic use—similar to scoring tools in eosinophilic esophagitis—and highlights the potential of low-dose oral tacrolimus as a safe and effective treatment option for patients with moderate to severe ELP. Addressing this unmet need may improve disease recognition and long-term management.
Surveillance Endoscopy in Barrett’s Esophagus: Does It Work? Margaret J. Zhou, MD, MS Clinical Assistant Professor of Medicine, Division of…
Subcutaneous Guselkumab Is Effective for Both Induction and Maintenance of Crohn’s Disease Rahul Dalal, MD, MPH Instructor, Division of Gastroenterology,…
The authors highlight the 2025 ACG Guideline on malnutrition and nutritional recommendations in liver disease, emphasizing early screening, individualized nutritional goals, and targeted supplementation to improve outcomes across various etiologies and stages of chronic liver disease.
Can non-invasive fecal immunochemical tests be used to extend surveillance intervals for colonoscopy among Lynch syndrome patients?
EBGI summary reviews the 2025 SPHINX study published in Gut on endoscopic sphincterotomy to prevent post-ERCP pancreatitis after self-expandable metal stent placement for distal malignant biliary obstruction.
EBGI summary discussed a RCT from the Netherlands that examines neoplasia detection rates in individuals with IBD without active inflammation who were scheduled for endoscopic surveillance randomized to HD white-light endoscopy with segmental reinspection, single-pass HD white-light endoscopy, or to HD chromoendoscopy.